Neanderthals, Cro-Magnon Competed For Food

News July 20th, 2008

A 50,000-year record of mammals eaten by early humans in southwestern France shows that they basically hunted the same prey. The Neanderthal and Cro-Magnon competed for food.

The paper, published in the online Journal of Archaeological Science, counters the idea proposed by some scientists that Cro-Magnon, who were physically similar to modern man, supplanted Neanderthals because they were more skilled hunters as a result of some evolutionary physical or mental advantage.

“This study suggests Cro-Magnon were not superior in getting food from the landscape,” said lead author Donald Grayson, a University of Washington professor of archaeology. “We could detect no difference in diet, the animals they were hunting and the way they were hunting across this period of time, aside from those caused by climate change.

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28,000 Year-Old Ancestor DNA

News July 17th, 2008

Europe’s Ancestors: Cro-Magnon 28,000 Years Old Had DNA Like Modern Humans

Some 40,000 years ago, Cro-Magnons — the first people who had a skeleton that looked anatomically modern — entered Europe, coming from Africa. A group of geneticists, coordinated by Guido Barbujani and David Caramelli of the Universities of Ferrara and Florence, shows that a Cro-Magnoid individual who lived in Southern Italy 28,000 years ago was a modern European, genetically as well as anatomically.

The Cro-Magnoid people long coexisted in Europe with other humans, the Neandertals, whose anatomy and DNA were clearly different from ours. However, obtaining a reliable sequence of Cro-Magnoid DNA was technically challenging.

“The risk in the study of ancient individuals is to attribute to the fossil specimen the DNA left there by archaeologists or biologists who manipulated it,” Barbujani says. “To avoid that, we followed all phases of the retrieval of the fossil bones and typed the DNA sequences of all people who had any contacts with them.”

The researchers wrote in the newly published paper: “The Paglicci 23 individual carried a mtDNA sequence that is still common in Europe, and which radically differs from those of the almost contemporary Neandertals, demonstrating a genealogical continuity across 28,000 years, from Cro-Magnoid to modern Europeans.”

The results demonstrate for the first time that the anatomical differences between Neandertals and Cro-Magnoids were associated with clear genetic differences. The Neandertal people, who lived in Europe for nearly 300,000 years, are not the ancestors of modern Europeans.

–Public Library of Science (2008, July 16). Europe’s Ancestors: Cro-Magnon 28,000 Years Old Had DNA Like Modern Humans.
Science Daily

3000 Year-Old Caveman Relatives

News July 16th, 2008

caveman and UweEvery family has its skeletons in the cave, though, so Manfred Hucht-hausen, 58, a teacher, and 48-year-old surveyor Uwe Lange remained in celebratory mood. Thanks to DNA testing of remarkably well-preserved Bronze Age bones, they can claim to have the longest proven family tree in the world. “I can trace my family back by name to 1550,” Mr Lange said. “Now I can go back 120 generations.”

The good news for these two villagers in the Söse valley of Germany was that they have discovered their great-great-great-great- great-great-great-great- great-great-great-great- great-great-great-great- great-great-great-great- great-great-great-great- great-great-great-great- great-great-great-great- great-great-great-great- great-great-great-great- great-great-great-great- great-great-great-great- great-great-great-great- great-great-great-great- great-great-great-great- great-great-great-great- great-great-great-great- great-great-great-great- great-great-great-great- great-great-great-great- great-great-great-great- great-great-great-great- great-great-great-great- great-great-great-great- great-great-great-great- great-great-great-great- great-great-great-great- great-great-great-great- great-great-great-great- great-great-great-great- great-great-great-great- great-great-great grandparents — give or take a generation or two.

The bad news is that their long-lost ancestors may have grilled and eaten other members of their clan.

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Space Object Impact Kills Mammoths

News July 7th, 2008

EvidenceAt the end of the Pleistocene era, woolly mammoths roamed North America along with a cast of fantastic creatures – giant sloths, saber-toothed cats, camels, lions, tapirs and the incredible teratorn, a condor with a 16-foot wingspan.

About 12,900 years ago, these megafauna disappeared from the fossil record, as did evidence of human remains. The cause of the mass extinction and the human migration is a mystery. Now a team of scientists, including Brown University planetary geologist Peter Schultz, provides evidence that an asteroid impact likely caused the sudden climate changes that killed off the mammoths and other majestic beasts of prehistory.

In the Proceedings of the National Academy of Sciences, the international team lays out its theory that the mass extinctions in North America were caused by one or more extraterrestrial objects – comets or meteorites – that exploded over the Earth or slammed into it, triggering catastrophic climate change.

The scientists believe that evidence for these extraterrestrial impacts is hidden in a dark layer of dirt sometimes called a black mat. Found in more than 50 sites around North America, this puzzling slice of geological history is a mere three centimeters deep and filled with carbon, which lends the layer its dark color. This black mat has been found in archaeological digs in Canada and California, Arizona and South Carolina – even in a research site in Belgium.

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Comet Impact 13,000 Years Ago

News July 6th, 2008

comet

Two University of Oregon researchers proposed a startling new theory: that an extraterrestrial impact, possibly a comet, set off a 1,000-year-long cold spell and wiped out or fragmented the prehistoric Clovis culture and a variety of animal genera across North America almost 13,000 years ago.

Driving the theory is a carbon-rich layer of soil that has been found, but not definitively explained, at some 50 Clovis-age sites in North America that date to the onset of a cooling period known as the Younger Dryas Event. The sites include several on the Channel Island off California where UO archaeologists Douglas J. Kennett and Jon M. Erlandson have conducted research.

The theory is being discussed publicly, for the first time, in a news conference at the 2007 Joint Assembly of the American Geophysical Union being held in Acapulco, Mexico. Kennett is among the attendees who will be available to discuss the theory with their peers. The British journal Nature addressed the theory in a news-section story in its May 18 issue.

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Exploding Asteroid / OH, IN Evidence

News July 6th, 2008

Geological evidence found in Ohio and Indiana in recent weeks is strengthening the case to attribute what happened 12,900 years ago in North America — when the end of the last Ice Age unexpectedly turned into a phase of extinction for animals and humans – to a cataclysmic comet or asteroid explosion over top of Canada.

A comet/asteroid theory advanced by Arizona-based geophysicist Allen West in the past two years says that an object from space exploded just above the earth’s surface at that time over modern-day Canada, sparking a massive shock wave and heat-generating event that set large parts of the northern hemisphere ablaze, setting the stage for the extinctions.

Now University of Cincinnati Assistant Professor of Anthropology Ken Tankersley, working in conjunction with Allen West and Indiana Geological Society Research Scientist Nelson R. Schaffer, has verified evidence from sites in Ohio and Indiana – including, locally, Hamilton and Clermont counties in Ohio and Brown County in Indiana – that offers the strongest support yet for the exploding comet/asteroid theory.

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Mandible of Homo erectus Found

News July 6th, 2008

mandibleA complete mandible of Homo erectus was discovered at the Thomas I quarry in Casablanca by a French-Moroccan team co-led by Jean-Paul Raynal, CNRS senior researcher at the PACEA laboratory (CNRS/Université Bordeaux 1/ Ministry of Culture and Communication). This mandible is the oldest human fossil uncovered from scientific excavations in Morocco. The discovery will help better define northern Africa’s possible role in first populating southern Europe.

Left: Photograph of the fossil human mandible discovered May 15, 2008 at the Thomas I quarry site in Casablanca. (Credit: Copyright Jean-Paul Raynal)

A Homo erectus half-jaw had already been found at the Thomas I quarry in 1969, but it was a chance discovery and therefore with no archeological context. This is not the case for the fossil discovered May 15, 2008, whose characteristics are very similar to those of the half-jaw found in 1969.

The morphology of these remains is different from the three mandibles found at the Tighenif site in Algeria that were used, in 1963, to define the North African variety of Homo erectus, known as Homo mauritanicus, dated to 700,000 B.C.

The mandible from the Thomas I quarry was found in a layer below one where the team has previously found four human teeth (three premolars and one incisor) from Homo erectus, one of which was dated to 500,000 B.C. The human remains were grouped with carved stone tools characteristic of the Acheulian civilization and numerous animal remains (baboons, gazelles, equines, bears, rhinoceroses, and elephants), as well as large numbers of small mammals, which point to a slightly older time frame. Several dating methods are being used to refine the chronology.

The Thomas I quarry in Casablanca confirms its role as one of the most important prehistoric sites for understanding the early population of northwest Africa. The excavations that CNRS and the Institut National des Sciences de l’Archéologie et du Patrimoine du Maroc have led there since 1988 are part of a French-Moroccan collaboration. They have been jointly financed by the French Ministry of Foreign Affairs, the Department of Human Evolution at the Max Plank Institute in Leipzig (Germany), INSAP (Morocco) and the Aquitaine region.

Science Daily

DNA Retrieved from 1,000-year-old Vikings

News May 28th, 2008

Photobucket

Strands of 1,000-year-old DNA from 10 Viking skeletons have been retrieved, a team of scientists claims.

Of particular interest to us, is this paragraph from the research article:

Among present day Scandinavians Hg I constitutes <2%, however, we have previously observed a markedly higher frequency (10–20%) of Hg I in Danish Iron Age and Viking Age population samples. With the observation of Hg I for subject G6 this trend is also seen for the Viking population sample from Galgedil. Interestingly, Hg I shows a low frequency (1 out of 114 subjects) among other ancient populations in Italy, Spain, Great Britain, and early central European farmers.

If true, the achievement would be notable, since many researchers say it is impossible to recover authentic DNA from ancient humans.

Jorgen Dissing of the University of Copenhagen and colleagues say they retrieved the genetic material from the freshly sampled teeth of skeletons dating back to around A.D. 1000 and found at a non-Christian burial site called Galgedil on the Danish island of Funen.

Wearing protective suits, the researchers removed the teeth from the jaw at the moment the skeletons were unearthed, where they had lain untouched for 1,000 years. Subsequent laboratory procedures were carefully controlled to avoid contamination with modern human DNA.

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‘Mitochondrial Eve’ Research: Humanity Was Genetically Divided For 100,000 Years

News May 17th, 2008

The human race was divided into two separate groups within Africa for as much as half of its existence, says a Tel Aviv University mathematician. Climate change, reduction in populations and harsh conditions may have caused and maintained the separation.

Dr. Saharon Rosset, from the School of Mathematical Sciences at Tel Aviv University, worked with team leader Doron Behar from the Rambam Medical Center to analyze African DNA. Their goal was to study obscure population patterns from hundreds of thousands of years ago.

Rosset, who crunched numbers and did the essential statistical analysis for the National Geographic Society’s Genographic Project, said the team was trying to understand the timing and dynamics of the split into at least two separate groups.

“We wanted to look into the ancient history of our species. How did we live throughout most of our existence as a species? Did we live as one — or were we fractured into small groups? Until now, it wasn’t really clear,” says Rosset.

A Picture of the Ancient Past

Researchers believe that about 60,000 years ago, modern humans started their epic journeys to populate the world. This time period has been the primary focus of anthropological genetic research. However, relatively little is known about the demographic history of our species over the previous 140,000 years in Africa.

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Ice Man Relations

News May 7th, 2008

Dorothy Rosenberg’s sister called her recently to give her some news about a long-lost relative - a really, really long-ago-lost relative.

Rosenberg, 80, who belongs to the Alaskan Tlingit tribe, learned through DNA testing that an iceman who died 200 to 300 years ago in the wilds of British Columbia is one of her ancestors.

The iceman could be a legendary Arctic trader celebrated in tribal lore. But even if he’s not, the twenty-something man - found draped in squirrel pelts and wearing a hat made of roots - is being welcomed as kin by his California cousins.

“We are also Jewish,” said Aaron Rosenberg, Dorothy Rosenberg’s youngest son who lives in Hollywood. “We are the best of both tribes.”

Three sheep hunters found the human remains in a melting glacier in 1999 on land in British Columbia, part of the traditional territory of the Champagne and Aishihik First Nations. The tribe named him Kw day D n Ts’inchi, meaning “Long Ago Person Found” in the Southern Tutchone language.

DNA testing recently traced the remains to 17 people in Alaska and Canada, including Dorothy Rosenberg’s sister, Harryet Rappier, who lives in Juneau, Alaska. She called recently to deliver the news.

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Early Human Split

News April 26th, 2008

Ancient humans started down the path of evolving into two separate species before merging back into a single population, a genetic study suggests. The genetic split in Africa resulted in distinct populations that lived in isolation for as much as 100,000 years, the scientists say. This could have been caused by arid conditions driving a wedge between humans in eastern and southern Africa.

It would be the longest period for which modern human populations have been isolated from one another. But other scientists said it was still too early to reconstruct a meaningful picture of humankind’s early history in Africa. They argue that other scenarios could also account for the data.

At the time of the split - some 150,000 years ago - our species, Homo sapiens, was still confined to the African continent.

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Human Near-Extinction

News April 24th, 2008

Human beings may have had a brush with extinction 70,000 years ago, an extensive genetic study suggests. The human population at that time was reduced to small isolated groups in Africa, apparently because of drought, according to an analysis released Thursday.

The report notes that a separate study by researchers at Stanford University estimated the number of early humans may have shrunk as low as 2,000 before numbers began to expand again in the early Stone Age.

“This study illustrates the extraordinary power of genetics to reveal insights into some of the key events in our species’ history,” Spencer Wells, National Geographic Society explorer in residence, said in a statement.

“Tiny bands of early humans, forced apart by harsh environmental conditions, coming back from the brink to reunite and populate the world. Truly an epic drama, written in our DNA.”

Previous studies using mitochondrial DNA — which is passed down through mothers — have traced modern humans to a single “mitochondrial Eve,” who lived in Africa about 200,000 years ago.

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Czar / Anastasia DNA Tests

News April 6th, 2008

DNA test results to be announced within months on bone fragments found in Russia last year could prove that none of Czar Nicholas II’s family escaped execution in the Bolshevik Revolution — not even Anastasia, the teenage princess whose identity various women have claimed over the decades.

Evgeny Rogaev, who heads a genetic research team working in Moscow and at the University of Massachusetts Medical School in Worcester, is not immune to the effect his work could have on how his fellow Russian citizens view that turbulent chapter in their history.

He keeps pictures of the royal family carefully tucked inside a folder near charts of DNA sequences, but does not display them. Likewise, he shields any sight of the remains from everyone except the other researchers, out of respect for whomever the remains represent.

“Murders occurred. Children were murdered,” he said this week, choosing his words carefully. “I will not make a show of it. That is my ethics.”

For Rogaev, a professor at UMass and Moscow State University, ensuring the accuracy of the DNA tests is paramount.

“In an expert work, it cannot be about emotions. It must be about collection of scientific evidences, and that is why this DNA is so powerful to study,” he said.

Rogaev is reviewing the genetic material at the request of the Russian Federation Prosecutor’s Office as part of its reopened investigation of the deaths of the royal family.

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DNA Shows 70,000 Year Link

News April 4th, 2008

A 30-year-old systems administrator from a small village close to Madurai in Tamil Nadu has been identified as one of the direct descendants of the first ever settlers in India, who had migrated from the African coast some 70,000 years ago.

The DNA of Virumandi Andithevar, one of the circa 700 inhabitants of Jothimanickam village, matched the white chromosome marker scientifically labeled “M130″, which is a gene found only among the descendants of the African migrants who had spread across the world tens of thousands of years ago. “This young man and 13 members of his nine-generation clan carried the same marker in their genes. It means that his ancestors in all probability settled in this village several generations ago,” said Prof. Rm Pitchappan, who led a team of scientists tracking the “M130″ DNA.

“M130 is actually present sporadically among the population along the Western Ghats and around Madurai,” said Dr Pitchappan, who heads the School of Biological Sciences at Madurai Kamaraj University. His research was part of the “Genographic Project”, a global initiative launched by National Geographic and a team of reputed scientists for unraveling the mystery of human migration. “The genetic studies carried out using M130 told us about the first human migration to India. We identified the marker of the first coastal migration in our Madurai samples. The search took us to Virumandi, who belongs to the Piramalai Kallar community, whose DNA matched M130, establishing him as one of the direct descendants of the first migrant from the African coast, who must have come here some 70,000 years ago,” Dr Pitchappan said.

Virumandi is elated with the news. “This is God’s gift to me, to be told that my roots go back to 70,000 years. They used to say that our village of 700 people had spawned from just three ancestors and I had often wondered from where and when they came. Now I have the answer — they came 70,000 years ago from Africa,” Virumandi said.

It took five years to establish the DNA link between Virumandi and the first migrants to the subcontinent. The studies also proved that though the migration to India took place some 70,000 years ago, the first settlement in the South happened about 10,000 years later.

“More than half of the Australian aborigines carry this M130 gene. The marker is also present among some people in Philippines and the tribals of Malaysia,” said Dr Pitchappan.

The Genographic Project will gather all data in collaboration with indigenous and traditional people around the world. The public is invited to join the project by purchasing a Genographic Project public participation kit. The proceeds from the sales go to further field research and the Genographic Legacy Fund, which in turn supports indigenous conservation and revitalization projects.

from The Asian Age

Petrified Poop in Paisley Cave

News April 3rd, 2008

Poop shows humans lived in North America more than 14,000 years ago

Discovered in a cave in Oregon, fossil feces yielded DNA indicating these early residents were related to people living in Siberia and East Asia, according to a report in Thursday’s online edition of the journal Science.

“This is the first time we have been able to get dates that are undeniably human, and they are 1,000 years before Clovis,” said Dennis L. Jenkins, a University of Oregon archaeologist, referring to the Clovis culture, well known for its unique spear-points that have been studied previously.

Humans are widely believed to have arrived in North America from Asia over a land-bridge between Alaska and Siberia during a warmer period. A variety of dates has been proposed and some are in dispute.

Few artifacts were found in the cave, leading Jenkins to speculate that these people stayed there only a few days at a time before moving on, perhaps following game animals or looking for other food.

The petrified poop — coprolites to scientists — is yielding a look at the diet of these ancient Americans, Jenkins said. While the analysis is not yet complete, he said there are bones of squirrels, bison hair, fish scales, protein from birds and dogs and the remains of plants such as grass and sunflowers. The oldest of several coprolites studied is 14,340 calendar years old, said co-author Eske Willerslev, director of the Centre for Ancient Genetics at Denmark’s University of Copenhagen.

“The Paisley Cave material represents, to the best of my knowledge, the oldest human DNA obtained from the Americas,” he said. “Other pre-Clovis sites have been claimed, but no human DNA has been obtained.”

The date for the new coprolites is similar to that of Monte Verde in southern Chile, where human artifacts have been discovered, added Willerslev. Jenkins said it isn’t clear exactly who these people living in the Oregon caves were, since there were few artifacts found. He said there was one stone tool, a hand tool used perhaps to polish or grind or mash bones or fat.

“We are not saying that these people were of a particular ethnic group. At this point, we know they most likely came from Siberia or Eastern Asia, and we know something about what they were eating, which is something we can learn from coprolites. We’re talking about human signature,” he said.

“If you are looking for the first people in North America, you are going to have to step back more than 1,000 years beyond Clovis to find them,” Jenkins said.

The Clovis culture has been dated to between 13,200 and 12,900 calendar years ago and is best known by the tools left behind.

Michael Waters, director of the Center for the Study of the First Americans at Texas A&M University, said the find, along with indications of human presence at other locations, adds to the evidence for a pre-Clovis human presence in North America.

“The genetic evidence from the coprolites from Paisley Caves is also consistent with the current genetic data for the peopling of the Americas — that the earliest inhabitants of the Americas came from Northeast Asia,” added Waters, who was not part of the research team.

Jenkins said that discoveries like those in the Oregon caves “help us to reconstruct the American past.”

“Our heritage is really important and it is important to the majority of the American public. If you don’t know where you come from, it’s hard to have a feeling of community, of participation.”

To make sure the Oregon cave material hadn’t been contaminated with modern DNA, the researchers tested more than 50 people who worked at the site. The DNA testing indicated that the feces belonged to Native Americans in two groups that can be traced to Siberia and East Asia.

In their paper the researchers dated the coprolites at 12,300 “carbon years” before the present. Prior to 3,000 years ago, carbon years differed from calendar years, resulting in the date of approximately 14,300 calendar years for the coprolites.

The research was funded by the Museum of Natural and Cultural History, University of Oregon; Association of Oregon Archaeologists and the Marie Curie Actions program.
from Yahoo News article

A New Y Haplogroup Tree?

News April 1st, 2008

Scientists reshape Y chromosome haplogroup tree gaining new insights into human ancestry.

Wednesday, April 2, 2008 –The Y chromosome retains a remarkable record of human ancestry,since it is passed directly from father to son. In an article published online today in GenomeResearch (www.genome.org), scientists have utilized recently described genetic variations on thepart of the Y chromosome that does not undergo recombination to significantly update and refinethe Y chromosome haplogroup tree. The print version of this work will appear in the May issue ofGenome Research, accompanied by a special poster of the new tree.

Human cells contain 23 pairs of chromosomes: 22 pairs of autosomes, and one pair of sexchromosomes. Females carry a pair of X chromosomes that can swap, or recombine, similarregions of DNA during meiosis. However, males harbor one X chromosome and one Ychromosome, and significant recombination between these dissimilar sex chromosomes does not occur. Therefore, the non-recombining region of the Y chromosome (NRY) remains largelyunchanged over many generations, directly passed from father to son, son to grandson, and so on, along with genetic variations in the NRY that may be present. Scientists can use geneticvariations, such as single nucleotide polymorphisms (SNPs), on the Y chromosome as markers of human ancestry and migration.

In 2002, the Y Chromosome Consortium (YCC) constructed a tree of 153 haplogroups based upon 243 unique genetic markers. In this report, researchers led by Dr. Michael Hammer of the University of Arizona recognized the need to revisit the Y chromosome haplogroup tree and incorporate the latest data. “The YCC effort in 2002 was a landmark in mapping the then known 300 or so Y-linked SNPs on a single tree, and getting the community to use the same nomenclature system,” explains Hammer. “The rate of SNP discovery has continued to increase
over the last several years, as are publications on Y chromosome origins and affinities. While this new information is useful, ironically it also brings with it the danger of introducing more chaos into the field.”

Hammer’s group integrated more than 300 new markers into the tree, which allowed the resolution of many features that were not yet discernable, as well as the revision of previous arrangements. “The major lineages within the most common African haplogroup, E, are now all sorted out, with the topology providing new interpretations on the geographical origin of ancient sub-clades,” describes Hammer. “When one polymorphism formerly described as unique, but recently shown to have reversed was replaced by recently reported markers, a sub-haplogroup of haplogroup O, the most common in China, was considerably rearranged,” explains Fernando
Mendez, a co-author of the study.

In addition to improving the resolution of branches, the latest reconstruction of the tree allows estimates of time to the most recent common ancestor of several haplogroups. “The age of [haplogroup] DE is about 65,000 years, just a bit younger than the other major lineage to leave Africa, which is assumed to be about 70,000 years old,” says Hammer, describing an example of the fine resolution of age that is now possible. “Haplogroup E is older than previously estimated, originating approximately 50,000 years ago.”

Furthermore, Hammer explains that this work has resulted in the addition of two new major haplogroups, S and T, with novel insights into the ancestry of both. “Haplogroup T, the clade that Thomas Jefferson’s Y chromosome belongs to, has a Middle Eastern affinity, while haplogroup S is found in Indonesia and Oceania.”

“More SNPs are being discovered, and we anticipate the rate to increase with the 1000 Genomes Project,” says Hammer, referring to the wealth of human genetic variation data that will soon be available. While this report represents a significant advance in mapping ancestry by Y chromosome polymorphisms, it is certain that future discoveries will necessitate continual revisions to the Y chromosome haplogroup tree, helping to further elucidate the mystery of ourorigins.

FTDNA Press Release

Drugstore Paternity Tests

News April 1st, 2008

Good idea?

After two decades, Sean Reid of Surrey, British Columbia, discovered that he had a son. Fred Turley of Des Plaines, Ill., learned he didn’t have a daughter. And Wendy Lieb of Lewis Center, Ohio, made certain that her son was not the claimed father of a girlfriend’s baby.

All three situations were determined by a $29.99 kit on a drugstore shelf named Identigene by Sorenson Genomics of Salt Lake City.
Sales in three western states — Washington, Oregon and California — were so brisk last fall that Rite Aid Corp. expanded the product this week to some 4,300 stores in 30 states across the country.

“Everyone is purchasing the tests because they’re curious,” said Fogg, who expects to sell at least 52,000 tests this year. “They’re looking to establish questions about their own child or their own paternity.”

But for genetics experts, drugstore marketing of DNA testing raises questions of accuracy and ethics.

“From our perspective, direct-to-consumer genetic tests raise all the same issues for lax government oversight, potentially misleading or false advertising and the potential for making profound medical decisions on the basis of poorly interpreted or understood results,” said Rick Borchelt, a spokesman for the Genetics and Public Policy Center at Johns Hopkins University.

Reliability

The paternity kits have taken their place on store shelves next to other diagnostic tests that don’t rely on DNA, including those for pregnancy, HIV and blood sugar, said Michael S. Watson, executive director of the American College of Medical Genetics.

Unlike genetic tests for health conditions, tests that use DNA to determine paternity are fairly simple to provide and fairly easy to interpret, said Watson. They’re subject to limited oversight, however, with no review required by the Food and Drug Administration and no certification required under the federal Clinical Laboratory Improvement Amendments, or CLIA.

The Identigene kit includes swabs for collecting cell samples from the inside of the cheeks of the child and the alleged father. Collection of the mother’s cells is optional, but strongly recommended to strengthen the results. The swabs are packaged and mailed to the Sorenson laboratory in Salt Lake City where they’re analyzed.

The Sorenson lab is accredited by the AABB, the agency formerly known as the American Association of Blood Banks.

Results are reported online, by phone or by mail in three to five business days. They come back as a probability figure that verifies paternity with 98 percent to 99 percent accuracy, Watson said.

Total cost is about $150, including the price of the kit and a $119 laboratory processing fee. For another $200, users can purchase validated tests that meet legal requirements for determining paternity, Fogg said.

Legal Concerns

But Susan Crockin, a lawyer who specializes in reproductive technology, said consumers shouldn’t count on the tests standing up in court.

“The jury’s still very much out on these tests in terms of reliability and establishing a chain of custody,” said Crockin, a consultant for the Johns Hopkins public policy center.

Most of the users who have been buying the kits — which have gone on sale for as low as $17.99 — don’t plan to use the results to resolve legal issues, Fogg acknowledged. Instead, most are looking to answer social questions. And that’s where the complexity comes in.

Because the cell samples are taken in private, there’s the potential for fraud and deception, noted Charo, the ethics expert.

“I can imagine rather peculiar circumstances in which somebody has a swab taken without their knowledge,” she said. “It raises questions about informed consent.”

Even when people do consent, the results can be unsettling. Watson estimates that between 5 percent and 10 percent of genetic tests he’s conducted show a child is not related to the presumed father.

“It could break up families,” Watson said. “Some will be broken because that was the goal. Others will be broken up and that wasn’t the goal.”

But people who’ve used the at-home tests swear by the ease, the accuracy — and the results.

1852 Body Linked to the Present

News March 30th, 2008

A Smithsonian Team Gives Unearthed Body a Name

William T. White, 14 years of age, from Accomack County on Virginia’s Eastern Shore, died in 1852 of pneumonia. All dressed up in a white burial suit and put into an iron coffin, he was left behind when the cemetery where he was buried in Northwest Washington moved a decade after his death. And there he stayed, forgotten, while the city continued to grow above him - and 155 years passed by.

He was accidentally unearthed by a construction crew in 2005 and researchers at the Smithsonian Institution vowed to find out who he was. But this historical drama / detective story took a couple of wrong turns in the process.

Smithsonian anthropologist Douglas W. Owsley stated the boy had been about five feet tall and probably sickly because of a hole between two chambers in his heart. He had been buried in a cemetery that probably belonged to Columbian College, the precursor to George Washington University, in what is now Columbia Heights, and had been a student at the college preparatory school when he died Jan. 24, 1852.

It’s All In The Case

Back to the beginning though - the research began with the coffin; the Fisk and Raymond “metallic burial case” was a big clue. Such airtight coffins were expensive, most affordable by the rich and were popular between 1850 and 1860. It was opened in August 2005 to be examined by a team of pathologists.

The body was extremely well preserved and the fashion of pleated shirt and vest with cloth-covered buttons, flared trousers, darned socks and ankle-length underdrawers seemed to indicate the 1850s. An autopsy concluded that the boy probably died of lobar pneumonia.

The grave was found in the now-residential neighborhood of Columbia Heights. Columbian College had once been there, and a page from a 1970 history of George Washington University stated that the old college had a cemetery. Further research showed that the original cemetery was moved in 1866 from the periphery of the college grounds to the main campus. And it was during this move that the iron coffin was probably left behind. This might have been because the tombstone was absent or had been misplaced during the Civil War, when the college was the site of two sprawling military hospitals, the researchers said.

Dead Ends

The team began reading lists of obituaries from the 1850s compiled from local newspapers and jumped too quickly at an item in the May 27, 1852 edition of Washington’s Daily National Intelligencer that had an obituary for Lemuel P. Bacon, 12, the son of Columbian’s president, Joel Bacon. It seemed perfect - “seemed.”

With samples of the dead boy’s mitochondrial DNA ( which can be traced and matched via female descendants over many generations), Hull-Walski and Scott developed a Bacon family tree and located a descendant in Texas. But that descendant’s DNA did not match. Dead End Number One. It is never that easy, as we genealogical researchers know!

Continuing with the obits, the Jan. 28, 1852 edition of the Intelligencer carried a brief obituary for a William Taylor White, of Accomack, who had died “at college hill” four days earlier. In a digest of old wills for Accomack County, they found one in which a guardian had left White money for his education. This time, Scott said, “we really felt like we had the right person.”

However, the course of genealogy never runs smoothly - when the researchers saw that the same digest contained the will of a Levin White, who had a son named William T., they “assumed” he must have been the boy’s late father. But when a descendant of Levin White was located in Baltimore and her DNA did not match. Dead End Number Two.

The team had also found an obituary for a William Henry White, who had died Sept. 29, 1852, at the age of 14. There was no connection to the college, but the boy’s father, Mathias, had been a Pennsylvania Avenue undertaker who used Fisk and Raymond coffins. Again a descendant was traced, this time to suburban Maryland - but again the DNA did not match. Dead End Number Three.

The Tide Turns

It was now summer 2006, and the team had been working on the case for a year. The boy’s body was being preserved at the museum, encased in a white body bag inside a metal cooler, but no closer to knowing who he was.

That Spring, a clue came by accident. Searching through a computer database of the Washington Intelligencer, Hull-Walski stumbled on another notice of the death of William T. White. Not an obituary, but a heartfelt “resolution” drawn up by his college friends, expressing their anguish at the loss of one who “was bound to us by the tenderest ties of friendship.” Somehow it had not turned up in prior research, but it reinforced to Hull-Walski that, despite the DNA, William T. White had to be the coffin boy. She showed the notice to Scott. “It’s him,” she told her colleague. But where had they gone wrong?

“So we started again,” Hull-Walski said. She appealed to colleagues on the Eastern Shore, where White was born, explaining the problem and asking for help and a local genealogist called her with the news that the Levin White she thought was William’s father, and whose family tree she had traced, was from a different White clan.

Later, two acquaintances visiting an Accomack records office found an 1850 court document that referred to White’s status as an orphan — and listed the name of his deceased father, William A. White. There was the research mistake, Hull-Walski realized, and that’s why the DNA didn’t match. “It was a relief,” she said.

The Tie That Binds

The identification was made after museum researchers, led by Deborah Hull-Walski and Randal Scott, figured out that the youth might be White, constructed a 788-person family tree — a diagram that stretched the length of a wall — and tracked down a descendant in Lancaster, Pa.

Linda Dwyer, 64, a night clerk in a convenience store, matched to a sample of DNA taken from the boy’s left shinbone. “I think it’s awesome,” Dwyer said, adding that she believes she is White’s great-great-great-grandniece. “The whole technology of finding me and putting it all together. . . . It’s so cool.”

Yes it is Linda, yes it is.

source: Wash Post Article

1.3 Million Year-Old Human Ancestor

News March 26th, 2008

MADRID, Spain - A small piece of jawbone found in a cave in Spain is the oldest known fossil of a human ancestor in Europe. This also shows that people lived on the continent much earlier than previously believed.

This fossil was found last year at Atapuerca in northern Spain, along with stone tools and animal bones, and is up to 1.3 million years old. That would be 500,000 years older than remains from a 1997 find that prompted the naming of a new species: Homo antecessor, or Pioneer Man, possibly a common ancestor to Neanderthals and modern humans — and this find seems to be from the same species, researchers said.

The timing of the earliest occupation of Europe by humans that emerged from Africa has been controversial for many years. Some archeologists believe the process was a stop-and-go one in which species of hominins — a group that includes the extinct relatives of modern humans — emerged and died out quickly only to be replaced by others, making for a very slow spread across the continent, Carbonell said in an interview.

Until now the oldest hominin fossils found in Europe were the Homo antecessor ones, also found at Atapuerca, but at a separate digging site, and a skull from Ceprano in Italy.

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Good(k)night in America

News March 26th, 2008

Two brothers slain by Native Americans — and a niece who was kidnapped and made an American Indian bride.

If Obama’s great-great-great-great-great-great-grandfather Christian Gutknecht had an adventurous life, it’s lost to history. But the fate of his brothers and their families could fill a TV mini-series.

Christian and his brothers, Hans Michael and George, all emigrated to the New World from Germany on separate ships in the mid-1700s. All three went by Goodnight once they arrived.

Both Hans — also known as John Michael, or just Michael — and George were slaughtered by American Indians in separate late-18th century attacks in frontier Kentucky.

“They pioneered into the Kentucky wilderness among the earliest of those who went there; the blood of both brothers, spilled in Indian warfare, helped make it ‘the dark and bloody ground,’ ” wrote descendant S.H. Goodnight in The Good(k)night Family (Gutknecht) Family in America (1936).

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